Translational and Molecular Medicine – DIMET
The PhD in Translational and Molecular Medicine (DIMET) is an inter-departmental program aimed at promoting the translation of basic and applied research into clinical settings.
The cultural challenge of the post-genomic era relies on the understanding of the cellular and molecular mechanisms at the basis of human diseases in order to design new therapeutic strategies. This goal requires professional profiles with a robust background in basic research, but also equipped to bridge the gap between laboratory and clinical investigation. Dimet addresses the increasing demand of such new models of innovative inter-sectorial training programs in Biomedicine, in line with the EU Horizon 2020 Program.
Dimet builds “translational” professional profiles with a robust background in basic research and the capacity of rapidly transferring new knowledge from basic sciences to bio-medicine, in order to generate new advanced diagnostic and therapeutic applications. Therefore, research in public or private sector, in biotechnology enterprises, private/public agencies working at the interface between basic research and healthcare represent possible career opportunities.
DIMET organizes a coordinate and cross-disciplinary training to form highly qualified PhDs and MDs with potential bench-to-bedside round trips. The participation to DIMET of private Research Institutes allows to expose students to different research environments, approaches and methodologies. DIMET students are strongly encouraged to spend a period abroad to improve their research and to promote students’ international networking. To this end DIMET is open to participate to international educational programs, such as MariaSxxCurie Actions.
The DIMET program covers three main interconnected areas:
-Cellular and molecular mechanisms.
-Clinical and regenerative medicine.
-Technological platforms, nanomedicine and diagnosis.
The structure and programs of the PhD Course in Translational and Molecular Medicine (DIMET) takes into account the multidisciplinary nature of modern Biology and Medicine, and the need to familiarize biologists with medical problems and physicians with basic biology. Thus, the research activity at DIMET may start either from medical problems which may be dealt with by new biological developments, or from basic studies and discoveries which may, in principle, be applied to medicine. The approximately equal participation of clinicians and basic investigators (including experts in chemistry, statistics, etc), and the organization of common seminars and teaching activities for all of the students (and teaching faculty) ensures that fruitful interactions between the two components will develop.
Hence, as indicated in the cartoon summarizing DIMET activities, research and teaching programs will develop from strong interactions between a fundamental broad area of “Cellular and Molecular Mechanisms” providing expertise in many areas of biological investigation, and more specialized areas, such as “Neuroscience and Neuromuscular Disorders", “Oncology and Haematology Disorders”, “ Immunological and Infective Disorders” and “Cardiovascular and Pulmonary Disorders”. At a higher level, the translation of knowledge will be implemented into therapeutic and diagnostic programs, within other broad areas called “Clinical and Regenerative Medicine” and “Technological Platforms, Nanomedicine and Diagnosis”. Therefore, the proposed PhD program will foster advanced genomics, proteomics, cellular and instrumental biotechnology and their applications to experimental medicine, contributing to forward its translational medicine applications to human diseases.