GUGLIELMETTI SIMONE DOMENICO
Research
SDG's scientific activity center on applied microbiology and microbial biotechnology, with a primary emphasis on food, probiotics, and host-associated microorganisms. The overarching goal is to deepen our understanding of microbe-host interactions, contribute to the development of functional foods, and advance biotechnological strategies relevant to the food industry. Key research interests encompass microbial genetics, immunomodulation, microbial adhesion, metataxonomics, metabolomics, and the functional implementation of microbial strains as probiotics and live biotherapeutics.
Publications
Barbaro, M., Bianco, F., Cremon, C., Marasco, G., Bonomini, F., Palombo, M., et al. (2025). Lactiplantibacillus plantarum (CECT7484 and CECT7485) and Pedioccoccus acidilactici (CECT7483) enhance actin cytoskeleton and CYP1A1 expression restoring epithelial permeability alterations induced by irritable bowel syndrome mediators. GUT MICROBES, 17(1) [10.1080/19490976.2025.2452235]. Detail
Florez, C., Zaragoza, J., Prather, J., Parra, M., Davis, J., Vargas, A., et al. (2025). Postbiotic Supplementation Increases Amino Acid Absorption from Plant-Based Meal: A Placebo-Controlled, Randomized, Double-Blind, Crossover Study. PROBIOTICS AND ANTIMICROBIAL PROTEINS [10.1007/s12602-025-10480-y]. Detail
Marino, M., Mignozzi, S., Michels, K., Cintolo, M., Penagini, R., Gargari, G., et al. (2024). Serum zonulin and colorectal cancer risk. SCIENTIFIC REPORTS, 14(1) [10.1038/s41598-024-76697-z]. Detail
Mantegazza, G., Duncan, R., Telesca, N., Gargari, G., Perotti, S., Riso, P., et al. (2024). Lactic acid bacteria naturally associated with ready-to-eat rocket salad can survive the human gastrointestinal transit. FOOD MICROBIOLOGY, 118(April 2024) [10.1016/j.fm.2023.104418]. Detail
Perruzza, L., Heckmann, J., Rezzonico Jost, T., Raneri, M., Guglielmetti, S., Gargari, G., et al. (2024). Postnatal supplementation with alarmins S100a8/a9 ameliorates malnutrition-induced neonate enteropathy in mice. NATURE COMMUNICATIONS, 15(1) [10.1038/s41467-024-52829-x]. Detail
Research projects
Awards
Research and teaching assignments
- Attivita' didattica - Adjunct Professor of General Microbiology - Tampere University of Technology, 2015 - 2020