Simone

GUGLIELMETTI SIMONE DOMENICO

Position:
vice direttore di dipartimento (DIPARTIMENTO DI BIOTECNOLOGIE E BIOSCIENZE)
Role
Full Professor  
Academic disciplines
Agricultural, Food and Environmental Microbiology (AGRI-08/A)
Scientific-Disciplinary Group:
AGRICULTURAL, FOOD AND ENVIRONMENTAL MICROBIOLOGY (07/AGRI-08)
Email
[email protected]

Research

SDG's scientific activity center on applied microbiology and microbial biotechnology, with a primary emphasis on food, probiotics, and host-associated microorganisms. The overarching goal is to deepen our understanding of microbe-host interactions, contribute to the development of functional foods, and advance biotechnological strategies relevant to the food industry. Key research interests encompass microbial genetics, immunomodulation, microbial adhesion, metataxonomics, metabolomics, and the functional implementation of microbial strains as probiotics and live biotherapeutics.

Publications

  • Pierallini, E., Mantegazza, G., Pizzelli, B., Angelini, F., Cozzi, S., Duncan, R., et al. (2025). Beyond viability: comparative functional evaluation of live and inactivated industrial biomasses of probiotic lactobacilli. Intervento presentato a: 18th International Scientific Conference on Probiotics, Prebiotics, Gut Microbiota and Health - IPC2025, Athens. Detail

  • Taverniti, V., D'Incecco, P., Farris, S., Jonsen, P., Skovsted Eld, H., Sørensen, J., et al. (2025). The Capacities of the Probiotic Strains L. helveticus MIMLh5 and L. acidophilus NCFM to Induce Th1-Stimulating Cytokines in Dendritic Cells Are Inversely Correlated with the Thickness of Their S-Layers. BIOMOLECULES, 15(7) [10.3390/biom15071012]. Detail

  • Mantegazza, G., Pizzelli, B., Pierallini, E., Angelini, F., Duncan, R., Guglielmetti, S. (2025). Isolation and characterization of novel bacterial strains for the development of fermented health-promoting plant-based products. Intervento presentato a: 13th Probiotics, Prebiotics & New Foods 2025, Roma, Italy. Detail

  • Duncan, R., Mantegazza, G., Gargari, G., Angelini, F., Russo, R., Guglielmetti, S. (2025). In vitro assessment of the impact of astragalus, pineapple stem 2 and bergamot extracts on the human fecal bacteria. In FEMS MICRO 2025 Abstract Book (pp.1040-1040). Detail

  • Guglielmetti, S., Boyte, M., Smith, C., Ouwehand, A., Paraskevakos, G., Younes, J. (2025). Commercial and regulatory frameworks for postbiotics: an industry-oriented scientific perspective for non-viable microbial ingredients conferring beneficial physiological effects. TRENDS IN FOOD SCIENCE & TECHNOLOGY, 163(September 2025) [10.1016/j.tifs.2025.105130]. Detail

Full list

Research projects

We all eat microbes: diet as reservoir of microorganisms that preserve the ecosystem services of the human gastrointesti nal microbiota (the μbEat project)
Year: 2023
Call: Bando PRIN 2022
Grantors: MINISTERO DELL'UNIVERSITA' E DELLA RICERCA (MUR)

Awards

Research and teaching assignments

  • Attivita' didattica - Adjunct Professor of General Microbiology - Tampere University of Technology, 2015 - 2020