Simone

GUGLIELMETTI SIMONE DOMENICO

Position:
Vice Direttore di Dipartimento (DIPARTIMENTO DI BIOTECNOLOGIE E BIOSCIENZE)
Role
Full Professor  
Academic disciplines
Agricultural, Food and Environmental Microbiology (AGRI-08/A)
Scientific-Disciplinary Group:
AGRICULTURAL, FOOD AND ENVIRONMENTAL MICROBIOLOGY (07/AGRI-08)
Email
[email protected]

Research

SDG's scientific activity center on applied microbiology and microbial biotechnology, with a primary emphasis on food, probiotics, and host-associated microorganisms. The overarching goal is to deepen our understanding of microbe-host interactions, contribute to the development of functional foods, and advance biotechnological strategies relevant to the food industry. Key research interests encompass microbial genetics, immunomodulation, microbial adhesion, metataxonomics, metabolomics, and the functional implementation of microbial strains as probiotics and live biotherapeutics.

Publications

  • Brunelli, L., Perotti, S., Gargari, G., De Vitis, V., Mantegazza, G., Ferrari, R., et al. (2025). Genetic and phenotypic stability of Lacticaseibacillus paracasei DG (DSM 34154) over 10 years of industrial production. APPLIED AND ENVIRONMENTAL MICROBIOLOGY [10.1128/aem.02394-24]. Detail

  • Mignozzi, S., De Pinto, G., Guglielmetti, S., Riso, P., Cintolo, M., Penagini, R., et al. (2025). Role of aspirin on colorectal cancer risk and bacterial translocation to bloodstream. PLOS ONE, 20(3), 1-13 [10.1371/journal.pone.0319750]. Detail

  • Florez, C., Zaragoza, J., Prather, J., Parra, M., Davis, J., Vargas, A., et al. (2025). Postbiotic Supplementation Increases Amino Acid Absorption from Plant-Based Meal: A Placebo-Controlled, Randomized, Double-Blind, Crossover Study. PROBIOTICS AND ANTIMICROBIAL PROTEINS [10.1007/s12602-025-10480-y]. Detail

  • Barbaro, M., Bianco, F., Cremon, C., Marasco, G., Bonomini, F., Palombo, M., et al. (2025). Lactiplantibacillus plantarum (CECT7484 and CECT7485) and Pedioccoccus acidilactici (CECT7483) enhance actin cytoskeleton and CYP1A1 expression restoring epithelial permeability alterations induced by irritable bowel syndrome mediators. GUT MICROBES, 17(1) [10.1080/19490976.2025.2452235]. Detail

  • Cirio, S., Salerno, C., Guglielmetti, S., Mezzasalma, V., Sarrica, A., Kirika, N., et al. (2025). In Vivo Study on the Salivary Kinetics of Two Probiotic Strains Delivered via Chewing Gum. MICROORGANISMS, 13(4) [10.3390/microorganisms13040721]. Detail

Full list

Research projects

We all eat microbes: diet as reservoir of microorganisms that preserve the ecosystem services of the human gastrointesti nal microbiota (the μbEat project)
Year: 2023
Call: Bando PRIN 2022
Grantors: MINISTERO DELL'UNIVERSITA' E DELLA RICERCA (MUR)

Awards

Research and teaching assignments

  • Attivita' didattica - Adjunct Professor of General Microbiology - Tampere University of Technology, 2015 - 2020