ALBERTI PAOLA

Role
Assistant Professor  
Academic disciplines
Anatomia umana (BIO/16)
Office phone
Room:
  • U08, Floor: 1, Room: 1034
Reception hours

On appointment ([email protected]).

Biography

MD, PhD, Board in Neurology.

Her main expertise is related to peripheral nervous system diseases, especially Chemotherapy Induced Peripheral Neurotoxicity (CIPN). She is an active member of the Toxic Neuropathy Consortium (TNC), part of the Peripheral Nerve Society (PNS). During the Residency in Neurology, she was a visiting fellow at Johns Hopkins University (Prof. D.R. Cornblath, MD) to refine her knowledge of neurophysiological techniques. Since 2015 she has been pursuing an interest for preclinical research and joined the Experimental Neurology Unit (ENU, University of Milano-Bicocca) team, where she completed the PhD program in Neuroscience (2019). Her PhD project was focused on Oxaliplatin Induced Peripheral Neurotoxicity in preclinical models: she introduced advanced neurophysiological techniques, nerve excitability testing, to ENU after having learnt them from Prof H. Bostock, (UCL, London). She was a visiting fellow at University of Baltimore (Prof. S.G. Dorsey and Prof C. Renn) where learned DRG recordings in preclinical models.

Since August 2016 she is a consultant Neurologist at San Gerardo Hospital (ASST Monza, Italy): she is the treating physician for outpatients affected by CIPN (Ambulatorio di Fragilità Neurologica). She is the PI in this Center for the INTERNATIONAL CHEMOTHERAPY-INDUCED NEUROTOXICITY (CIPN) ASSESSMENT AND VALIDATION STUDY (ICAVS, see: International CIPN Assessment and Validation Study – Full Text View – ClinicalTrials.gov) which involves 30 Centers around the globe (US, Canada, South America, Africa, India, Asia, Australia). In the same Center, she is also PI of the CIPN COST study (www.cipncare.com), aiming at ascertaining socio-economic burden related to CIPN (awarded a 115,000 euros grant, by UNIMIB), and of the NEUPER study, aiming at ascertain efficacy of physical treatment to reverse sensory ataxia due to polyneuropathy. 

In 2022 she received a personal grant of 249,980 euros from Fondazione Cariplo to carry out a 3-year preclinical project, entitled Sodium-calcium exchanger (NCX) and ion channels: pivotal elements leading to axonal damage in peripheral nerves?, with the aim of investigating mechanisms of axonopathy with a translational approach.

Publications

  • Hertz, D., Tofthagen, C., Rossi, E., Bernasconi, D., Lim, J., Carlson, M., et al. (2024). Patient perceptions of altering chemotherapy treatment due to peripheral neuropathy. SUPPORTIVE CARE IN CANCER, 32(1 (January 2024)) [10.1007/s00520-023-08209-0]. Detail

  • Alberti, P., Argyriou, A., Bruna, J., Damaj, M., Faithfull, S., Harding, A., et al. (2024). Considerations for establishing and maintaining international research collaboration: the example of chemotherapy-induced peripheral neurotoxicity (CIPN)—a white paper. SUPPORTIVE CARE IN CANCER, 32(2) [10.1007/s00520-023-08301-5]. Detail

  • Alberti, P., Mastropietro, A., Rizzo, G., Taccogna, M., Bontempi, P., Schiavi, S., et al. (2023). High resolution MRI in exploring peripheral nerve anatomy and axonal damage in rodent models. In Abstract book. Detail

  • Alberti, P. (2023). Oxaliplatin Induced Peripheral Neurotoxicity: From Bed to Bench Side and Vice Versa. In Abstract book. Detail

  • Alberti, P., Canta, A., Chiorazzi, A., Pozzi, E., Ballarini, E., Rodriguez-Menendez, V., et al. (2023). Acute and chronic Oxaliplatin-induced peripheral neurotoxicity: two sides of the same coin. In Meeting proceedings. Detail

Research projects

Grant Starter School - II edition
Year: 2023
Grantors: IBRO - INTERNATIONAL BRAIN RESEARCH ORGANISATION (Organisation Internationale de Recherche sur le Cerveau)
Sodium-calcium exchanger (NCX) and ion channels: pivotal elements leading to axonal damage in peripheral nerves?
Year: 2022
Grantors: FONDAZIONE CARIPLO