LONGHESE MARIA PIA

Role
Full Professor  
Academic disciplines
Genetics (BIOS-14/A)
Room:
  • U03, Floor: 5, Room: 5053
  • U03, Floor: 5, Room: 5049
  • U03, Floor: 5, Room: 5055

Publications

  • Pizzul, P., Casari, E., Rinaldi, C., Gnugnoli, M., Mangiagalli, M., Tisi, R., et al. (2024). Rif2 interaction with Rad50 counteracts Tel1 functions in checkpoint signalling and DNA tethering by releasing Tel1 from MRX binding. NUCLEIC ACIDS RESEARCH, 52(5), 2355-2371 [10.1093/nar/gkad1246]. Detail

  • Casari, E., Pizzul, P., Rinaldi, C., Gnugnoli, M., Clerici, M., Longhese, M. (2023). The PP2A phosphatase counteracts the function of the 9-1-1 axis in checkpoint activation. CELL REPORTS, 42(11 (28 November 2023)) [10.1016/j.celrep.2023.113360]. Detail

  • Rinaldi, C., Pizzul, P., Casari, E., Mangiagalli, M., Tisi, R., Longhese, M. (2023). The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase. NUCLEIC ACIDS RESEARCH, 51(4 (28 February 2023)), 1783-1802 [10.1093/nar/gkad062]. Detail

  • Pizzul, P., Casari, E., Gnugnoli, M., Rinaldi, C., Corallo, F., Longhese, M. (2022). The DNA damage checkpoint: A tale from budding yeast. FRONTIERS IN GENETICS, 13 [10.3389/fgene.2022.995163]. Detail

  • Casari, E., Gnugnoli, M., Rinaldi, C., Pizzul, P., Colombo, C., Bonetti, D., et al. (2022). To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand Breaks. CELLS, 11(20), 1-22 [10.3390/cells11203224]. Detail

Research projects

Harnessing functions, regulation and interactions of DNA double-strand break sensor proteins for targeted therapies – II annualità
Year: 2023
Grantors: FONDAZIONE AIRC
Harnessing functions, regulation and interactions of DNA double-strand break sensor proteins for targeted therapies - 1° annualità
Year: 2022
Grantors: FONDAZIONE AIRC
PNRR per la Missione 4, componente 2 Investimento 1.1- Avviso 104/2022 | Chromatin topological transitions at telomeres and at DNA double strand breaks
Year: 2022
Call: Bando PRIN 2022
Grantors: MINISTERO DELL'UNIVERSITA' E DELLA RICERCA (MUR)
Interplay between genotoxic and mechanical stress in neurodegeneration
Year: 2021
Call: Decreto Direttoriale n.1628 del 16-10-2020 - Bando PRIN 2020
Grantors: MINISTERO DELL'UNIVERSITA' E DELLA RICERCA (MUR)
Targeting DNA double-strand break repair in cancer: genetic and biochemical approaches to study DNA end resection - V annualità
Year: 2021
Call: 2017-005 - Call for Proposals 2017 Investigator Grant (IG)
Grantors: FONDAZIONE AIRC

Awards

Awards

  • Premio Giovanni Magni, Fondazione Adriano Buzzati-Traverso, 1997

Scientific fellowships

  • Fellow - European Molecular Biology Organization (EMBO), 2008
  • Socio effettivo o corrispondente - Associazione Genetica Italiana, 2005

Editorial boards

  • Membro del Comitato Editoriale - DNA REPAIR, 2021