PIAZZA FABRIZIO
- U08, Floor: 2, Room: 2040
Biography
He is leading translational research aimed to improve patient care by accelerating the development and delivery of personalised healthcare, including personalised therapies and diagnostics, applied to neurodegenerative, neuroimmunological and cerebrovascular disorders, particularly on the immune-mediated mechanisms and the amyloid-related imaging abnormalities (ARIA) in the pathogenesis of both rare diseases, i.e. Cerebral Amyloid Angiopathy-related inflammation (CAA-ri), and during immunotherapy trials of Alzheimer’s disease.
He has more than 10 years experience in the discovery and validation of diagnostic, prognostic and therapeutic biomarkers and tools.
Dr Piazza is the founding Member and Coordinator of the inflammatory Cerebral Amyloid Angiopathy and Alzheimer’s disease βiomarkers International Network (iCAβ), a World-Wide Consortium involving 35 leading Centers of Excellence on AD and CAA from 12 different Countries, established in 2012
The validation of biomarkers of ARIA, as well as the definition of clinico-therapeutic recommendations to guide CAA and AD immunotherapy trials, is the main goal of the the biomarkARIA Research Project (P.I. Dr. Piazza) and iCAB International Network , the largest worldwide effort aimed at deciphering the pathogenetic mechanisms of CAA-ri and ARIA in a translational and cooperatively-open design between Academia and pharma companies.
FB page Link: https://www.facebook.com/icabinternational
WebSite: https://sites.google.com/site/icabinternationalnetwork/
Publications
- Piazza, F., & Bengt, W. (2016). Amyloid-Related Imaging Abnormalities (ARIA) in Immunotherapy Trials for Alzheimer’s Disease: Need for Prognostic Biomarkers?. JOURNAL OF ALZHEIMER'S DISEASE, 52(2), 417-420. Detail
- Auriel, E., Charidimou, A., Gurol, M., Ni, J., Van Etten, E., Martinez-Ramirez, S., et al. (2016). Validation of Clinicoradiological Criteria for the Diagnosis of Cerebral Amyloid Angiopathy-Related Inflammation. JAMA NEUROLOGY, 73(2), 197-202. Detail
- Difrancesco, J.C., Longoni, M., & Piazza, F. (2015). Anti-Aβ autoantibodies in amyloid related imaging abnormalities (ARIA): candidate biomarker for immunotherapy in Alzheimer’s disease and cerebral amyloid angiopathy. FRONTIERS IN NEUROLOGY, 6. Detail
- Piazza, F., Greenberg, S.M., Savoiardo, M., Gardinetti, M., Chiapparini, L., Raicher, I., et al. (2013). Anti-Aβ autoantibodies in cerebral amyloid angiopathy-related inflammation: Implications for amyloid-modifying therapies. ANNALS OF NEUROLOGY, 73(4), 449-458. Detail
- Piazza, F., Galimberti, G., Conti, E., Isella, V., Perlangeli, M.V., Speranza, T., et al. (2012). Increased tissue factor pathway inhibitor and homocysteine in Alzheimer's disease. NEUROBIOLOGY OF AGING, 33(2), 226-233. Detail
Research projects
Awards
Awards
- AAIC Fellowship, AAIC, 2014
- ADPD Faculty Award, International Conference on Alzheimer's and Parkinson's disease, 2013
- Premio Perusini, SINdem, 2013
- International Society of NeuroImmunology (ISNI), International Society of NeuroImmunology (ISNI), 2012
Scientific fellowships
- Socio effettivo o corrispondente - ISTAART PIA, Alzheimer's Association, 2023
- Componente del Consiglio/Comitato Direttivo - European Alzheimer's Disease Centers of Excellence Network (EADC), 2023
- Fellow - ISTAART PIA, Alzheimer's Association, 2022
- Componente del Consiglio/Comitato Direttivo - European Alzheimer's Disease Centers of Excellence Network (EADC), 2022
- Componente del Consiglio/Comitato Direttivo - European Alzheimer's Disease Centers of Excellence Network (EADC), 2021
- Socio fondatore - ISTAART PIA, Alzheimer's Association, 2021
Editorial boards
- Membro del Comitato Editoriale - EXPERIMENTAL AND MOLECULAR PATHOLOGY, 2023
- Direttore di rivista, collana editoriale, enciclopedia - JOURNAL OF ALZHEIMER'S DISEASE, 2015
Research and teaching assignments
- Ricercatore universitario a t.d. - Università degli Studi di MILANO-BICOCCA, 2018 - 2019
- Attivita' di insegnamento - Corso: LAUREA MAGISTRALE IN BIOTECNOLOGIE MEDICHE, Insegnamento: MODELLI SPERIMENTALI IN PATOLOGIA, Modulo: APPLICAZIONI IN NEUROLOGIA - Università degli Studi di MILANO-BICOCCA, 2008 - 2009
- Ricercatore universitario a t.d. - Università degli Studi di MILANO-BICOCCA, 2019 - 2022
- Professore a contratto - Corso: BIOTECNOLOGIE MEDICHE, Insegnamento: MODELLI SPERIMENTALI IN PATOLOGIA, Modulo: APPLICAZIONI NELLE MALATTIE DEL SISTEMA NERVOSO - Università degli Studi di MILANO-BICOCCA, 2011
- Professore a contratto - LAUREA MAGISTRALE IN BIOTECNOLOGIE MEDICHE, Insegnamento: 10 - Modelli sperimentali in patologia, Modulo: 10-Applicazioni nelle malattie del Sistema Nervoso - Università degli Studi di MILANO-BICOCCA, 2008 - 2009
- Professore a contratto - Corso: BIOTECNOLOGIE MEDICHE, Insegnamento: MODELLI SPERIMENTALI IN PATOLOGIA, Modulo: APPLICAZIONI NELLE MALATTIE DEL SISTEMA NERVOSO - Università degli Studi di MILANO-BICOCCA, 2009 - 2010
Congresses/Conferences
- Program committee - Nomina come membro del panel multidisciplinare per l’elaborazione della LINEA GUIDA: “DIAGNOSI E TRATTAMENTO DELLE DEMENZE” dell'ISS nell'ambito del Piano Nazionale Demenze del 2024(Italia), 2023